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they are given vitamins C and E to boost their antioxidant levels, and bicarbonate to correct metabolic acidosis.

GHK-CU IN THE PREVENTIVE THERAPY OF DIABETES Reactive oxygen species can induce cellular changes and influence the development of diabetes and its complications

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Methods In this study, we design a two-in-one ferroptosis-inducing nanoplatform using iron-based metal-organic framework (MOF) that combines iron supply and GPX4 deactivation by loading the small molecule buthionine sulfoxide amine (BSO) to block de novo GSH biosynthesis, which can achieve sustainable GSH elimination and dual ferroptosis amplification

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