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Elevated levels of HMGB1 and its receptors, RAGE and TLR4 proteins, were found in the lung tissue of smoking COPD patients [107], and CS-induced HMGB1 secretion may lead to insulin resistance [108]
doi: 10.3390/ijms21249683 37
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Rieger, Varsha Allampalli, Jamal Hasoon, Kazi N
