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AI has shown tremendous performance in structure-based drug discovery because of its ability to develop robust ML and DL models on structural and biochemical data to predict protein-ligand interactions, outperforming conventional high-throughput screening with high efficiency and accuracy

As increased mitochondrial levels of glutathione (GSH) might contribute to a change in seizure susceptibility, we quantified changes of absolute GSH levels in the brain by in vivo 1H magnetic resonance spectroscopy (1H MRS) and correlate that with degree of seizure control in patients on KD

This is often due to technique, local histamine response, or irritant effects from reconstitution practices

The V3-V4 region of the 16S rRNA gene was amplified using the primers MPRK341F (59-ACTCCTACGGGAGGC AGCAG-39) and MPRK806R (59-GGACTACHVGGG TWTCTAAT-39) with barcoding

doi: 10.1016/j.molmed.2021.06.014 51 Mikulska-RuminskaKAnthonymuthuTSLevkinaAShrivastavaIHKapralovAABayrHet al

This protein is a type II transmembrane glycoprotein encoded on chromosome 4 (4p15.32) and consists of three domains: an intracellular domain (N-terminus) of 21 amino acids, an alpha-helix transmembrane domain and an extracellular domain (C-terminus) of 256 amino acids