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The only benefit may be the possibility of pyruvate decarboxylation by the pyruvate dehydrogenase complex (PDC) [96], which produces the equimolar amount of NADH

PubMed Central , Nutrients , vol

It was also identified in the frontal cortex of decayed AD cases in cortical A plaques, whereas other data revealed its capacity to colocalize not only with CD68, NF-B, and Il-1 in AD post-mortem cases, but also with both phosphorylated Tau (p-Tau) and A(42) in mice [105]

Histological examination shows a tumor with a multinodular growth pattern composed of nests and/or cords of large-sized epithelioid cells with abundant eosinophilic to amphophilic cytoplasm and large rounded nuclei with vesicular chromatin and prominent nucleoli (Figure 24)