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They can stimulate and inhibit IGF signalling by regulating its half-life, clearance, and modulating receptor interactions

Amplification of ErbB2 receptor tyrosine kinase is observed in 2030% of women with breast cancer

Magnolol also show the potential to increase the activity or expression of ACE-2, and thus may aggravate SARS-CoV-2 infection (Junior et al., 2021)

In simple terms: Oxidized form (no H): empty, ready to receive energy Reduced form (with H): carrying energy (electrons) So: NAD+ NADH = picks up electrons NADP+ NADPH = picks up electrons Reduced doesnt mean smaller or weaker it just means the molecule is fully loaded and ready to do work

Sun Q, Li Y, Shi L, et al

A physiological role for SOD1 in guarding against mitochondrial oxidative damage
