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One study, interestingly, given the interest in ammonia in ME/CFS, found L-carnitine may be able to reduce ammonia production during exercise

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In another study, EGCG was observed to suppress the expression of TNF, IL-1, IL-6, and inducible nitric oxide synthase (iNOS), restoring the levels of intracellular antioxidants against free radical-induced pro-inflammatory effects in microglia, nuclear erythroid-2 related factor 2 (Nrf2), and heme oxygenase-1 (HO-1) [143]

In addition, when the circulating L-carnitine concentration increases, as in the case of oral supplementation, the renal reabsorption of L-carnitine may become saturated, resulting in the increased urinary excretion of L-carnitine