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Human Clinical Trials: Analgesia Overall, vitamin C has proven a safe and effective adjunctive therapy for acute and chronic pain relief in various settings

Key Points Glucocorticoids modulate growth hormone (GH) secretion at both the hypothalamic and pituitary level Hypoadrenalism might cause GH deficiency that is reversible during glucocorticoid replacement therapy Testing for GH deficiency in patients with hypopituitarism should always be performed after adequate periods of cortisol replacement Chronic excess of glucocorticoids, either exogenous or endogenous, causes GH deficiency that might be involved in metabolic and cardiovascular complications Treatment with recombinant GH could be considered in children and adults with glucocorticoid-induced GH deficiency This is a preview of subscription content, access via your institution Access options Subscribe to this journal Receive 12 print issues and online access 186,36 per year only 15,53 per issue Buy this article Purchase on SpringerLink Instant access to the full article PDF

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Other peptides may act only within the nervous system and are referred to as neuropeptides

2018] Walsh W, Wiggins M, Fadale P, Ehrlich M (1995) Effects of a delayed steroid injection on ligament healing using a rabbit medial collateral ligament model

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