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P-glycoprotein is localized to the apical surface of polarized cells that line the tubules or ducts or lumen of these organs, and thus provides such cells with a mechanism for extruding xenobiotic molecules that are recognized by the transporter, or for impeding uptake of these molecules (delaying absorption) (see Fig

Interaction of ganoderic acid on HIV related target: molecular docking studies

It is integrative and multisystemic

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