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It can be used to tighten skin and improve cellulite following weight loss

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1 The fat-oxidation study (ob/ob and lean mice)

An average weight loss of -8.1 kg and -10.2 kg was attained at the end of 56 weeks with phentermine 75 mg plus topiramate 460 mg, and phentermine 150 mg plus topiramate 920 mg, respectively