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Phosphatidic Acid PA, often referred to as phosphatidate (see Figure 1), represents the simplest phospholipid structure and tends to accumulate in membranes in relatively minor proportions, owing to the activity of lipid phosphate phosphohydrolases [28,29]

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Immune signaling emerges as a central conduit for microbiota-host interactions, with microbial metabolites and structural components influencing immune homeostasis across both mucosal and systemic compartments (Macpherson et al., 2023)