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Some disorders of intracellular cobalamin metabolism (cblC, cblD-MMA/Hcy, cblF, and cblJ) do not only compromise the synthesis of methylcobalamin, but also the synthesis of adenosylcobalamin, cofactor of the enzyme methylmalonyl-CoA mutase, leading to elevated concentrations of both tHcy and methylmalonic acid (MMA)

Acetyl-l-carnitine can also be converted back and forth to l-carnitine within the body and shuttles between cytosol and mitochondria (Fig

These results suggest that maintained regulation of various antioxidant systems allows compensatory mechanisms for mitigating long-term neuroanatomical and clinical impacts

Leguina-Ruzzi A: Therapeutic targets of glutamine in parenteral nutrition: a medical science review

Man K, Kutyavin VI, Chawla A

In this reaction, vitamin B 12 is needed to convert homocysteine to methionine