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Additionally, given that treatment is most effective if given early in the disease course or before patients become overtly symptomatic (Dzieyc et al., 2014), there is an increasing use of molecular diagnostics in first degree relatives of patients with WD to identify known homozygous or compound heterozygous mutations in such individuals (Ala et al., 2007

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Iron deficiency anemia reduces thyroid peroxidase activity in rats
