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Bremelanotide (PT-141), derived from Melanotan II, is a synthetic peptide developed for its role in treating sexual dysfunction in both men and women (Clayton et al., 2016)

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Contaminants or incorrect amino acid sequences can render the compound ineffective or cause unpredictable results

Meanwhile, NF-B (consisting of c-Rel, RelA (p65), RelB, p50/p105, and p52/p100) together with an inhibitor of NF-B kinase (IKK) proteins regulates many physiological processes, such as inflammation, innate- and adaptive-immune responses, and cell death [94,95]