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Complex II (cytochrome reductase) catalyzes this process where the Fe 3+ present in the cytochrome is reduced to Fe 2+
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It can also be a sign of liver problems or a lack of protein in your diet 13

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Potent inhibition of human steroid 5alpha-reductase (EC 1.3.1.30) by 3-androstene-3-carboxylic acids.Bioorg.Med.Chem.1989,17, 372-376 81
