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By using LAIP and DfN strategies, MRD tracking helps detect genomic and phenotypic changes before clinical relapse starts

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and can be induced by iron starvation, complement Fe-uptake yeast mutant, and mediate the remobilization of Fe from vacuolar stores, which is crucial for seed germination during early Fe deficiency period (Lanquar et al., 2005, Thomine et al., 2000)

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