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Start with the underlying science: Canine Skin & Coat Framework A structured view of how skin, coat, and nail health are maintained across collagen synthesis, lipid balance, and barrier function

Nature 575 , 693698 (2019)

Roche '66 Anna Maria Rochler P'21 Douglas M

Author contributions RS gave the study idea and designed it, and corrected the drafted manuscript

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The iron regulatory protein/iron-responsive element (IRP/IRE) system senses cellular iron levels and dynamically coordinates the expression of genes such as TFR1 and FPN ( 2.4 Lipid metabolic remodelinga key determinant of cellular susceptibility The phospholipid composition of cellular membranes directly determines susceptibility to ferroptosis