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By randomizing the order of the interventions (L-carnitine and placebo) and ensuring a 1-week washout period between each treatment, the study controls for potential carryover effects

Thus, the theoretical time window for treatment will close when the edema transits to its resolution phase and AQP4 switches from being an influx route for water to support water efflux 572

The above mechanism can be seen in Figure 1

They found that the medication was well tolerated, and it quickly reduced serum LH concentrations in a dose-dependent fashion

[DOI] [PubMed] [Google Scholar] 102.Biswas S, Swift M, Field HJ

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