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Nature 592 , 784788 (2021)

Effect of simultaneous induction and inhibition of CYP3A by St Johns Wort and ritonavir on CYP3A activity

2023;133(5):e162315

This dosing asymmetry is well-documented in the peer-reviewed literature and is not a matter of interpretation

Another recurring limitation emerges on antioxidant-based interventions in ASD, constrained by a fundamental methodological gap: most clinical studies report behavioral or functional improvements without directly measuring oxidative-stress biomarkers

The homogenates were centrifuged at 20,400 g for 20 min at 4 C, and the resulting supernatants were appropriately diluted and used in the assays, which were conducted according to the manufacturers instructions