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Preclinical studies suggest that DSIP may affect the balance between wakefulness and sleep, as well as responses to stress and pain perception

In addition to pain, symptoms include a tingling or burning sensation, numbness, and muscle weakness

This customization can help optimize glycemic control while minimizing side effects

For detailed guidance on temperature excursions, see our article on what happens when tirzepatide gets warm

During the first weeks of GLP-1 therapy, many patients experience a temporary worsening of GI symptoms before they improve

However, its important to remember that these peptides are still being investigated in clinical trials to assess their efficacy and safety