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Ceramides are modified to form more complex sphingolipids by the addition of phosphate or carbohydrate groups to form sphingomyelins, cerebrosides, or gangliosides

While this dose is considerably higher than typical environmental residues (found in the range of micrograms per kilogram), it is intentionally used in high-dose toxicological models to elucidate mechanisms of toxicity and assess mitigation strategies under controlled conditions 41

Inhibition of ferroptosis alleviates atherosclerosis through attenuating lipid peroxidation and endothelial dysfunction in mouse aortic endothelial cell

from Washington University in St

Santos P, Herrmann AP, Benvenutti R, Noetzold G, Giongo F, Gama CS, et al

Potential neurologic manifestations of COVID-19