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(172) demonstrated in diabetic rat models that TMAO treatment exacerbated renal inflammation and fibrosis through activation of the NLRP3 inflammasome, promoting IL-1 and IL-18 release and increasing pro-fibrotic TGF-1 expression
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Palm, W
Animal model studies indicate that Toll-like receptors (TLRs) contribute to T-cell responses by recognizing AAV capsid antigens [107,108]
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