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A 2011 study published in the Journal of Cosmetic Dermatology similarly demonstrates that a decrease in Glutathione may spur the development of acne

marianum extract is due to the presence of silymarin which consists of a mixture of different flavonolignans including silybin, silychristin, silydianin, isosilychristin, and several other flavonolignans as minor biological compounds [12, 29,30,31,32,33,34,35,36]

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