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Research has found that carnitine deficiency can cause smooth muscle dysmotility (changes in speed, strength, or coordination) of the gastrointestinal tract (similar to what it does to muscle metabolism, causing muscle weakness), which can cause gastrointestinal discomfort and changes in the microbiota ( gut dysbiosis ), as well as constipation

Betaine can be obtained either from diet or synthesized from dietary choline in the liver and kidney

[DOI] [PubMed] [Google Scholar] Borbath I, de Barsy T, Jeanjean A, Hantson P
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Plasma fatty acid levels in autistic children