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For example, exercise can increase adiponectin levels by 260% in as little as one week

Deng Z, Zhou X, Lu J-H, Yue Z

Cancer Biol Ther 13:14251435

(2010) found that increasing supplemental dietary carnitine caused a significant reduction in percentage of abdominal fat but addition of carnitine had no effect on the percentages of carcass yield, breast muscle or thigh muscle
Across those human studies, the effects on body weight and fat mass are usually modest and depend on dose, form, and how L-carnitine is used alongside diet and training

It is believed that several of these mechanisms are interconnected and together are responsible for the progression of the disease
