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2025 May:134:108895

Phase I dose escalation trial of docetaxel plus curcumin in patients with advanced and metastatic breast cancer

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LDL-C promotes coronary calcification directly through oxidation and inflammatory pathways, depositing within the vascular wall to form plaques, which subsequently induce smooth muscle cell calcification and eventually lead to stable calcified plaques [66]

LDL-c continues to be important both due to its proven causal role in atherosclerosis as well as the consistent relationship found between LDL-c reduction and observed cardiovascular risk reduction

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