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In orthopedics, postmenopausal osteoporosis (PMOP) is associated with a significant decline in the diversity and abundance of intestinal microbial communities in a clinical study enrolling 106 individuals, while bone loss was positively correlated with the decrease in genera Allisonella , Klebsiella , and Megasphaera (13)

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TBUT results from twelve studies were not statistically significant (Std diff 0.211, 95% CI 0.017 to 0.440, p = 0.8350, I = 0%)

Shaking the vial can damage the fragile peptide chains, a process called denaturation