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Mitochondrial creatine kinase attenuates pathologic remodeling in heart failure

[DOI] [PMC free article] [PubMed] [Google Scholar] Mamiya P, Arnett A, Stein M

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This includes research into NSAID-induced gastric lesions, where its cytoprotective properties are examined, and models of Inflammatory Bowel Disease (IBD), where its anti-inflammatory and barrier-protective functions are explored

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Subcutaneous administration (which bypasses first-pass metabolism and delivers more peptide to target tissues) was not extensively tested in human trials, and this route is what most current research protocols use