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Intestinal lesions produced by prednisolone: prevention (cytoprotection) by 16,16-dimethyl prostaglandin E2
Typical changes of ferroptosis including massive lipid peroxidation, compromised antioxidant capability, and iron overload were found in db/db mice and high glucose/high fat -treated HK-2 cells, while dapagliflozin treatment significantly ameliorated the ferroptosis-related changes via attenuating over-activation of the hypoxia-inducible factor-1 (HIF-1) and heme oxygenase-1 (HO-1) axis in vivo and in vitro [19]

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Tissue repair The primary reason people look into BPC-157: studied preclinically for how it may influence soft-tissue healing in animal models

[DOI] [PubMed] [Google Scholar] 11.Ooi S.L., Green R., Pak S.C