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One-pot synthesis of cereblon proteolysis targeting chimeras via photoinduced C(sp2)-C(sp3) cross coupling and amide formation for proteolysis targeting chimera library synthesis

10.1016/j.freeradbiomed.2012.06.026 118 ShinW

Contrary to these results, striatal DA depletion and DA neuron loss increased after melatonin treatment of rotenone-induced Parkinsonism (Tapias et al., 2010)

David EA, Wai C, Correa AM, Hofstetter WL, Rice DC, Roth JA, Swisher SG , Walsh GL, Vaporciyan AA, Thall P, Mehran RJ

Discussion In this paper, we develop the first mathematical model of the GSH antioxidant system in the outer retina, capturing the most essential components for ROS creation, GSH production, oxidation in neutralizing ROS, and reduction as well as the diversion of glucose into the PPP to synthesize NADPH

& Braakhuis, A