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Although studies have shown that HO-1 co-localizes with G4 in the nucleus (within 40 nm), as confirmed by the proximity ligation assay (PLA), no direct evidence of a binding interaction has been provided (Krzeptowski et al., 2021)
doi: 10.1002/jcp.27431, 149 ZhaoJ.HeZ.WangJ

Primary familial xanthomatosis with involvement and calcification of the adrenals

Unlike other vitamins, Vitamin B12 absorption is dependent on a protein called intrinsic factor
In the decades that followed, as a result of the growing understanding of tumours, classical ncRNAs were the focus of extensive research

The findings could help elucidate the established link between infectious triggers like COVID-19 and EBV and the development of ME/CFS
