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According to the study, the combination of two powerful antioxidants, like ALA and SOD, produced considerable improvements in both subjective and objective metrics

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The peptide demonstrated safety and met primary efficacy endpoints, showing reductions in disease activity scores compared to placebo

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89 Genetic activation of Nrf2 in KCs of a murine model of Netherton syndrome also improved the skin barrier defect by reducing the expression of proinflammatory cytokines and upregulating the secretory leukocyte peptidase inhibitor (SLPI), which in turn inhibited kallikrein 7 and elastase 2 and increased the attachment of the stratum corneum by stabilizing desmosomes
