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Functionalization of AgNPs with biocompatible polymers such as chitosan or polyethyleneimine further improves stability and bioavailability while reducing cytotoxicity to human cells (Liao et al., 2019)
10.1038/521S1a [DOI] [PubMed] [Google Scholar] Calls A., Torres-Espin A., Tormo M., Martnez-Escard L., Bonet N., Casals F., et al

A randomized, double-blind, placebo-controlled trial reported a significant reduction in melanin indices after four weeks of supplementation with 500 mg/day, particularly in sun-exposed areas [12]
L.LeungY.ArfusoF.DharmarajanA

H., Lee, S

May 2016;15(1)doi:10.9734/ejmp/2016/26453 Mazzio E, Deiab S, Park K, Soliman KF
