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There are growing trend towards lifestyle and natural approaches to treating PCOS , which focus on a healthy diet, exercise, sleep, and managing stress levels in order to manage the condition

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For instance, microglia can activate astrocytes into a neurotoxic state by releasing mitochondrial fragments and damaged mitochondria, further mediating extracellular neuronal death in neuroinflammation (23)

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Bing H, Ma Y, Xu J, Ling Q, Duan Y, Zhao L (2025) Impact of methotrexate and 7-hydroxymethotrexate exposure on renal toxicity in pediatric non-Hodgkin lymphoma