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doi: 10.3390/cancers13112847 18 CatenaUDella CorteLRaffoneATravaglinoALucci CordiscoETeodoricoEet al

Glutathione has four major functions Immune Regulator (Immune System Enhancer) The immune system is dependent on Glutathione (GSH) for proper functioning and is considered the bodys frontline defense against infections, whether bacterial or viral

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At the onset of MS, pathogenic inflammatory T lymphocytes infiltrate the CNS, triggering an immune response that activates microglia and astrocytes, leading to acute inflammation

Conversely, studies have shown that CXCL10-neutralizing antibody treatment blocks CD8 + T cell skin recruitment, significantly inhibiting disease progression in vitiligo mouse models (102)

Intriguingly, the m 6 A demethylase FTO has been shown to inhibit SLC7A11 expression and thus trigger ferroptosis in an m 6 A-independent manner, attenuating the development of papillary thyroid carcinoma[162]