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A meta-analysis of 18 clinical trials involving 1,883 women with poor ovarian response undergoing IVF or intracytoplasmic sperm injection found supplementing with 75 mg DHEA daily for two to four months reduced the risk of miscarriage by 50%, increased the pregnancy rate by 53%, and increased successful births by 87%

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Hertenstein E, Trinca E, Wunderlin M, Schneider CL, Zst MA, Fehr KD, et al

A spontaneous sPDD model has been generated by causing a deficiency in the type I IFN signaling pathway Deletion of neuronal IFN/IFNAR result in oxidation, mutation, and deletion of mtDNA, which is subsequently released from the neuron

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10.1039/D5PM00079C [DOI] [Google Scholar] 93.Dalhaimer P, Florey B, Isaac S