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Highlights PAHs were detected in water, sediment, and biological samples across the Amazon, with concentrations influenced by anthropogenic activities

Neuroblastoma SH-SY5Y had a complete opposite behavior, being sensitive to hydrogen peroxide, but resistant to diamide

Princeton University Press Sterner RW, Elser JJ (2002) Ecological stoichiometry: the biology of elements from molecules to the biosphere

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Statistics and reproducibility Statistical significance was determined using independent t -test for immunohistochemical and western blot analyses, and one-way analysis of variance for cell cycle and apoptosis detection by GraphPad Prism 7.0 software (GraphPad, Inc., La Jolla, CA, USA)

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