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Later, Kettner et al

Apoptosis is induced by 1-methyl-4-phenylpyridinium ion (MPP+) in ventral mesencephalic-striatal co-culture in rat

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Epidemiology of Lyme disease

These neurotransmitters can initiate signaling cascades that result in depolarization of projecting neurons, a larger inward current, and the death of gamma-aminobutyric acid (GABA) interneurons, whose role is to modulate pain through the descending pain pathway, all of which enhance central sensitization [4,5]

This oxidative stress can lead to cellular damage if not adequately managed