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P428, P434 Yates C

L-serine synthesis from 3-PG is high in the brain (especially in astrocytes) and the kidneys

doi: 10.1016/j.expneurol.2015.12.022 151 CathcartSJAppelSHPetersonLEGreeneEPPowellSZArumanayagamASet al

The most active part of CHE is the carbon adjacent to the quaternary nitrogen, attacked by the nucleophiles, and responsible for this compounds observed toxicity

[Google Scholar] 13

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