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Additionally, at least five ancillary symptoms must be present, such as limb heaviness or generalized weakness, diminished concentration, or attention, decreased motivation or interest in usual activities, insomnia or hypersomnia, nonrestorative sleep, perceived need to struggle against inactivity, pronounced emotional response to fatigue, perceived short-term memory issues, or prolonged malaise following exertion (11)

Orthop Traumatol Surg Res

Molecualr Biology of the Cell

2010;(2):Cd007280

High plasma levels of LDL, remnants and possibly Lp(a) promote accumulation of inflammatory cells, including foam cells, enhancing atherosclerotic plaque formation

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