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The strategies aimed at preventing photo-aging include sun avoidance, sun protection using sunscreens to block or reduce skin exposure to UV radiation, retinoids in order to inhibit collagenase synthesis and to promote collagen production, and anti-oxidants, particularly in combination, to reduce and neutralize free radicals (FR)

10.1016/s0079-6107(99)00017-6 36 BarronL

As soon as the effect of these substances wears off, the body begins to gradually return to its normal metabolic rate

It is noted that the effects of various pharmacological agents which act to increase the production of nitric oxide, for example the substrate for formation of nitric oxide, the amino acid arginine, the stability of nitric oxide in the blood, or the effect of nitric oxide, may be used synergistically

29 patients received pregabalin at the standard dose of 150 mg three times a day (arm B)

Randomized controlled trial of oral glutathione supplementation on body stores of glutathione in healthy adults