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Potential risks Serious risks and adverse events include: Allergic reaction to the medications or dye used in the injection Shoulder infection Depigmentation of the skin around the injection site (a whitening of the skin) Local fat atrophy around the injection site (thinning of the skin) Rupture of a tendon located in the path of the injection Nerve damage near the shoulder joint Bleeding at the injection site In addition to the above, corticosteroid injections increase the risk of: High blood pressure High blood sugar Decreased immune function Decrease in bone mineral density Bone infection (osteonecrosis) Reproductive hormone imbalance Metabolic changes (eg, increased appetite, weight gain, and fluid retention) These risks are typically associated with higher doses of corticosteroids, multiple injections, and for people with underlying medical conditions such as diabetes and heart problems

10.4103/0973-1482.202886 [DOI] [PubMed] [Google Scholar] Panda S, Kar A (1998) Ocimum sanctum leaf extract in the regulation of thyroid function in the male mouse

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Frequency of use varies : some research protocols apply DSIP on an as-needed basis for sleep difficulties, while other studies explore short-term daily administration over 1 to 4 consecutive days

The vial is contaminated and should be discarded