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VRK2 promotes ER-to-Golgi trafficking of SLC7A11 and its expression on the cell membrane To explore the effect of VRK2 on the expression of SLC7A11, we first investigated mRNA level of SLC7A11 in VRK2 knockdown cells and found that VRK2 did not affect the transcription of SLC7A11 (Fig

Acknowledgements We thank Dave Primm (Department of Surgery, University of Texas Southwestern Medical Center) for his critical reading of the manuscript

In addition, the above findings indicate that DMSA monoesters are a superior treatment option to DMSA on its own in terms of eliciting recovery from altered biochemical variables and causing depletion of body lead and cadmium burden

Furthermore, the helical arrangement of ventricular myocardial fibers creates sufficient and coordinated forces to pump blood within the body

These complexes can deposit in tissues, initiating an inflammatory response and resulting in damage to multiple organs (46)

Cholesterol metabolism significantly contributes to cancer progression