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2014 PMC3913810 Pescovitz, MD

Lastly, while no significant difference was observed in the overall symptom score between groups, specific hyperthyroid symptoms were significantly lower in the intervention group, including irritability, tremor, mood lability, heat intolerance, and exertional dyspnea

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While future studies will help confirm the relevance of many of these findings in the mammalian brain, these results reinforce the notion that KBs have a broad array of non-metabolic biological effects that directly impinge on neurotransmission and neuronal excitability (Figure 1)