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4.8 Undesirable effects As most undesirable effects are based on post-marketing spontaneous reporting, frequency estimation is not possible

That information is more clinically useful than any preclinical peptide literature and it is available now, without waiting for human trial results that do not yet exist

Complete immobilization beyond what is necessary for fracture stability can actually impair healing by depriving the callus of the mechanical signals that guide remodeling

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Treatment of the incompetent great saphenous vein by endovenous radiofrequency powered segmental thermal ablation: first clinical experience

Surprisingly, deletion of PNPLA2 does not result in obesity, likely due to counter-regulatory mechanisms such as reductions in food intake and reduced PPAR signaling in adipose tissue (239)