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Description
Persistent increase in oxygen consumption and impaired neurovascular coupling after spreading depression in rat neocortex

By affixing lactate groups to lysine residues, histone Kla directly connects metabolic fluctuations with the regulation of gene expression, hence connecting metabolic conditions to epigenetic regulation
Special Handling Note: Disulphide Bond Stability The intramolecular disulfide bond between the two cysteine residues is a critical structural feature of this compound

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This is because physical movement tends to heighten the blood flow directed at the muscles, which is what we want before administering an IV drip
