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Cellular trafficking of nanotechnology-mediated mRNA delivery

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In addition, expression of the necroptosis markers phospho RIPK3 and phospho MLKL were decreased in Beas-2B cells transfected with GSR siRNA compared with control siRNA after treatment with the necroptosis inducers TNF, smac mimetic, and Z-VAD (Figure 6E)

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Specifically this is Cys 90 of the SdhA subunit has been shown to be S-glutathionylated using purified SdhA and liquid chromatography/tandem mass spectrometry