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A recent study on cardiomyocytes show that expression of IL-6 was increased in aged wild-type mice, while this increase was attenuated in aged IGF-1R knockout mice, suggesting an essential role of IGF-1R in regulating IL-6 expression and cardiomyocyte senescence [21]

In PD cases, comparable panels complexed BDNF with -synuclein and inflammatory cytokines also with excellent performance in predicting motor symptom progression

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Int J Mol Sci 13(7):83798387 Ke M et al (2012) The effect of astragalin on the VEGF production of cultured Mller cells under high glucose conditions

Studies show that whereas lower phosphorylated GSK3 correlates with the severity of depression, greater CREB activity and decreased BDNF levels are linked to AD, particularly in the moderate to severe stages of dementia

According to the TCM theory, the liver is associated with irritability, the liver is stored in blood and the kidney is stored in essence, and since essence and blood share the same origin, liver and kidney dysfunctions are also closely related to hearing loss
