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Consistent with in vivo experimental results, GSTM5 expression was decreased in LPS-exposed RA-FLSs

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In cases of excessive nitric oxide production, complete inhibition of cytochrome c oxidase has been shown to contribute to pathology

In other words, glutathione guards the NAD+ pool as well as the rest of the cell

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High levels of stress were also reported to be connected with disruptions in serotonergic-related pathways, the volume of some brain areas such as the hippocampus and prefrontal cortex, and epigenetic changes in genes such as BDNF [49,50,51]