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Lee SJ, Choi YJ, Kim HI, Moon HE, Paek SH, Kim TY, et al

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Navani stresses

Mechanical allodynia and axonal degeneration, but not cold hyperalgesia, were ameliorated by daily co-administration of Cystine [200 mg/kg orally (p.o.)] and Theanine (80 mg/kg p.o.)

This was evidenced by significant inhibition of key oxidative and inflammatory mediators, including myeloperoxidase and malondialdehyde levels

Regulatory challenges are significant as well, with guidelines for EV-based therapeutics still under development