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Instead of prediction, these methods are mostly used to investigate the underlying mechanisms involved in existing ADRs

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Walker RJ (1986)

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Yes, it is commonly studied in laboratory models related to muscle, tendon, and tissue repair mechanisms.

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Ca 2 enters mitochondria via the mitochondrial calcium uniporter in the IMM, activating dehydrogenases in the tricarboxylic acid cycle and enhancing OXPHOS and ATP production, ensuring energy supply matches demand in cardiomyocytes and regulating synaptic transmission and plasticity in neurons

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Results and therapeutic implications for cavopulmonary derivations]

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Curr Opin Ophthalmol 20:7378

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